Spanning over 3 millennia with one of the highest concentrations of architecture in the world, Rome is a transcendental influence on the world's culture. A city rich in history, academia, and arts, the Italian capital is considered as one of the oldest continuously-occupied cities in Europe, and has maintained its countless layers of history to become a perfect depiction of old meets new, earning its nickname of "The Eternal City".

Rome's historic center, which stretches from Piazza del Popolo to Piazza Venezia and from the the east bank of the Tiber up to Piazza di Spagna, is listed as a UNESCO World Heritage Site. Along with its historical significance, the presence of renowned contemporary architects and designers in the city has made Rome an influential design destination. In 2019, it was the 14th most visited city in the world, welcoming over 8.6 million tourists to make it the third most visited in the European Union, and the most popular tourist destination in Italy.

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While research seems intrinsic to the design process, architectural research is a professional path in itself, whose purpose is to highlight scientific evidence and explore alternatives outside of pre-established norms or empirical considerations. Its purpose is to create a framework of knowledge that can inform the design to reach objectively better outcomes. The following discusses the role and state of research in architecture, some prominent areas of inquiry, and the architects or institutions that dedicate their work to these subjects.

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